陈建波

一、个人简介

陈建波，男，1982年生，博士，副研究员，硕士研究生导师。中国中药协会人参属药用植物研究发展专业委员会委员。

研究方向：中药材精深加工关键技术研究与产品开发；中药材大健康产品设计与创制。

电话:13180844386

邮箱:chenjianbo00882@126.com

地址:长春市净月区聚业大街 4899号

二、主要工作经历

2014年—至今   中国农业科学院特产研究所  

2012年-2014年  韩国高立大学；药物化学；博士后

2008年-2012年  韩国忠南大学；药物化学；博士学位

2005年-2008年  吉林农业大学；中药学专业；硕士学位

2001年-2005年  吉林农业大学；中药学专业；学士学位

三、主要成果及奖励

主持吉林省自然基金面上项目“基于代谢通路AMPK/PGC-1/NRF-1调控线粒体生物合成探讨人参皂苷Rg5改善睡眠的机制研究”；吉林省科技厅项目项目“人参贮藏关键技术及对品质的影响”；中国农业科学院创新工程项目“适合工业化生产人参皂苷Rg3的方法及功能产品开发”；国家重点研发计划子课题“鹿茸加工炮制及质量标准研究”；以第一作者或者通讯作者在 Journal of Ginseng Research，Phytotherapy Research等国际期刊发表SCI文章15篇；授权国家发明专利3项；软件著作权2项；参编著作3部；参与修订吉林省地方标准“梅花鹿产品品质等级划分”1项；开发参眠片、人参鼻炎康等产品5款。

四、代表论文

1. Jian-Bo Chen, Mei-Jia Li, Xiao-Hui Huo, Tie-Jun Gong. Ginsenoside Rg5 Improves Sleep by Regulating Energy Metabolism inSleep-Deprived Rats. The American Journal of Chinese Medicine. 2023, 51, 1845–1864.

2. Jianbo Chen, Meijia Li, Xiaohui Huo, Zhiman Li, Di Qu, Jiyue Sha and Yinshi Sun. A Novel Process for One-Step Separation and CyclodextrinInclusion of Ginsenoside Rg5 from Ginseng Stem–Leaf Saponins(GSLS): Preparation, Characterization, and Evaluation of StorageStability and Bioactivity. Foods 2023, 12, 2349.

3. Jianbo Chen，Meijia Li, Yinshi Sun. Protection by ginseng saponins against cyclophosphamide-induced liver injuries in rats by induction of cytochrome P450 expression and mediation of the L-arginine/nitric oxide pathway based on metabolomics. Phytotherapy Research, Phytotherapy Research. 2021;35:3130–3144

4. Jianbo Chen, Meijia Li, Lixue Chen, Yufang Wang, Shanshan Li, Yuwei Zhang, Lei Zhang, Mingjie Song, Chang Liu, Mei Hua, Yinshi Sun. Effects of processing method on the pharmacokinetics and tissue distribution of orally administered ginseng. Journal of Ginseng Research, 2018, 42, 27-34..

5. Jianbo Chen，Meijia Li, Yinshi Sun. Neuroprotective effects of red ginseng saponins in scopolamine-induced rats and activity screening based on pharmacokinetics. Molecules,. 2019, 24, 2136-2149.

6. Jianbo Chen, Youngho Kim, Yongki Park, Youngjoo Byun and Jongseong Kang. Simultaneous Determination of Six Compounds in Wen-Pi-Tang-Hab-Wu-Ling-San Using an HPLC-DAD Method and Application in a Pharmacokinetic Study Journal of the Chinese Chemical Society, 2015, 62, 439-442.

7. Jianbo Chen, Lixue Chen, Meijia Li, Yinshi Sun. Quantitative determination of six steroid alkaloids by sensitive hydrophilic interaction liquid chromatography electrospray ionization mass spectrometry and its application to pharmacokinetic study in rats. Biomedical Chromatography, , 2019, 33, 4377-4384.

8. Kun Gao, Jianbo Chen. Effects of 60 Co-γ and Electron Beam Irradiation on Storage Quality of Panax ginseng. Food and Bioprocess Technology, 2018, 11, 1627-1638.

9. Jianbo Chen, Youngho Kim, Yongki Park, Youngjoo Byun and Jongseong Kang，Simultaneous Determination of Six Compounds in Wen-Pi-Tang-Hab-Wu-Ling-SanUsing an HPLC-DAD Method and Application in a Pharmacokinetic Study. J. Chin. Chem. Soc. 2015, 62, 439-442

10. Zhiman Li, Lijuan Zhao, Jianbo Chen, Chang Liu, Shanshan Li, Yinshi Sun. Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing  the neuroinflammatory response. Biochemical and biophysical research communication, 2020, 530, 658-664.

11. 陈建波，陈丽雪，孙印石. 莱菔子与人参配伍对人参抗疲劳及药代动力学的影响研究。中草药。2019, 11, 308-31

五、发明专利

1. 陈建波;李美佳;孙印石，人参皂苷RK1环糊精包合物及制备和改善睡眠的应用，专利号：ZL 2023 1 0376779.6

2. 陈建波;李美佳;孙印石，人参皂苷Rg5及制备和在制备过敏性鼻炎药物中的应用，专利号：ZL 2023 1 0314680.3

3. 陈建波;李美佳，人参挥发油贴膏片，国家实用新型专利 申请专利号：ZL201820680941.8